UPDATE: The Baltimore Sun reports that the train was carrying unknown chemicals but the smoke did not include toxic inhalants. "Still, a 20-block area around the accident was evacuated." Baltimore County Fire Chief John J. Hohman said the fire is expected to burn through the night. The only two people aboard the train were not injured. Also, see an updated timeline of the CSX freight train derailment and explosion.
"The driver of the trailer was extricated and taken to Maryland Shock Trauma center in serious but stable condition."
VIDEO: HOW IT HAPPENED...Officials say several nearby buildings collapsed, reports WBAL. People felt the blast 22 miles away.Authorities evacuated the immediate area as a precaution. The derailment is in the area of E. Biddle and 66th streets in Rosedale, near the 7500 block of Lake Drive.
The affected buildings are right next to the track where the train derailed. Workers ran out to look at the crash, saw flames, and immediately got into their cars and drove three blocks away. Then came the explosion. "It about brought us to our knees," said one man.
Hazmat crews are on the scene. It is not clear what kinds of chemicals were in the freight cars involved in this accident. One police officer reported having trouble breathing. However, live video shows personnel walking near the fire not wearing any kind of hazmat suits or breathing equipment.
"A huge explosion could be heard across the city, and a large tower of smoke can be seen from miles away," reports CBS Baltimore. "Police and fire crews are responding to the area after receiving numerous calls to 911. Details on this accident are still unfolding." NBC has live video of the derailed train in Baltimore County. More live coverage at ABC7 WJLA and WBAL TV.
SEE VIDEOS OF THE ACTUAL EXPLOSION.